Intrauterine growth restriction(IUGR) is the one important complications in the perinatal period, and associated with poor perinatal health outcomes. In animal fetuses, IUGR can be caused by factors that are of maternal, placental or fetal origin.The most common cause of IUGR is placental insufficiency. However, there is a range of issues that require further investigation or investigation in more than one models. The information collected different animal models of IUGR may contribute to investigating its pathogenesis and seeking effective ways. In this article, the authors review the experimental animal models of IUGR, including natural selection, the surgical ablation of the majority of endometrial caruncles, passive smoking, matemal undernutrition, ligation of an umbilical artery.