Abstract:Objective To establish a model of acute and chronic oviduct inflammatory infertility in rats infected with Staphylococcus aureus. Methods A 4 × 10 9 / mL S. aureus suspension was prepared. A total of 108 rats were randomly divided into a normal group, a model group, and a control group, with 36 rats in each. The model group was injected in the fallopian tube with the S. aureus suspension, and the control group was injected with saline in the fallopian tube. The morphology of the fallopian tube was observed on the 7th, 14th, 21st, and 28th days after surgery, and S. aureus culture and pathological examination were also performed. Results After the injection of S. aureus into the fallopian tube, acute oviduct inflammation emerged on postoperative days 7 and 21 to form chronic tubal inflammatory models, and on day 28 to form an oviduct inflammatory model of infertility. Conclusions The injection of 4 ×10 9 / mL S. aureus into rat oviduct successfully established an acute salpingitis and chronic tubal phlogistic sex infertility rat model.