Pathological significance of the starry sky pattern in tumors
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(Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences (CAMS); Comparative Medicine Center, Peking Union Medical College (PUMC); Key Laboratory of Human Disease Comparative Medicine, National Health and Family Planning Commission of the People’s Republic of China (NHFPC); Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine; Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious Diseases, Beijing 100021, China)

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R-33

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    Abstract:

    The starry sky pattern is a distinctive histological feature in lymphoid tissue and lymphoma. The cytoplasm of these histiocytes typically contains cellular remnants. Here, this review discusses the historical, pathophysiological and pathophysiological research of the starry sky pattern, which may contribute to establishment of a lymphoma animal model, development of radiation and drug therapies, and determination of doses.

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History
  • Received:January 02,2018
  • Revised:
  • Adopted:
  • Online: August 08,2018
  • Published: