Cardiovascular disease is still the world’s first cause of death, its morbidity and mortality rates are still increasing. Recent studies have shown that circular RNA is involved in the regulation of gene expression and plays a significant role in the pathogenesis of cardiovascular diseases. Circular RNA is a kind of special non-coding RNA, which can regulate the expression of genes at the level of post-transcription or transcription, then regulate various life activities as well as cardiovascular system diseases, becoming a latest research hot spot in the field of RNA. Nowadays, more and more attention is paid to the role of cyclic RNA in the development, early diagnosis, disease monitoring and other aspects of cardiovascular diseases. In this paper, we make an overview of the latest research on circRNAs from the aspects of genesis, function, and the relationship with cardiovas cular diseases, and so on.