Objective To establish a haemorrhoids model with the method of acid burns on rats''skin, and to study the pharmacological effects of Tongbianhuazhi Keli on this model. Method10mol /L hydrochloric acid burned the scratched skin around rats anus and the anal medial mucosa. Tongbianhuazhi Keli was orally administered to the rats for 10d. Then score the skin with macroscopic observation and light microscope. ResultPathological results showed that the haemorrhoids model was established successfully. And the pathologic changes on hydrochloric acid burned rats skin can be effectively restored by oral application of large and middle dose of Tongbianhuazhi Keli. Conclusion The haemo haemorrhoids model with the method of acid burns on rats skin was successful; Tongbianhuazhi Keli was effective to restore the rats skin of haemorrhoids model.