Objective To investigate the pattern feeding nutritional standard and breeding management of model animals.Methods In order to provide scientific method for oncology,the human liver cancer model was established by transplanted BALA/c nude mouse(nu/nu),and the growth was controlled by enhancing nutritional component and strength the feeding management.Results By feeding up and enhancing,the tumor growth of model animals was controlled gradually and survival constitution of animal was improved remarkedbly,and the bearing tumor survival time was delivered obviously.Conclusion The protein nutrition of feed could impact on survival constitution and effect of animal experimental,this have the effective significantly for establishment of other animal method.