Abstract:The argyrophil cells in digestive tract of Pelophylax nigromaculata were studied with the silver nitrate method of Grimelius.The argyrophil cells could be observed throughout the digestive tract,distributing between epithelial cells of mucosa and epithelial cells of glands,with the highest distributive density in pyloricus and lowest in duodenum.The morphology of argyrophil cells differs in accordance with distributive parts.Argyrophil cells might have endocrine,exocrine,paracrine functions;and configuration of argyrophil cells might be related to the pressure.;