A comparative study of auxiliary lipid-lowering function of Antarctic krill oil preventive and therapeutic administration
投稿时间:2018-03-20  修订日期:2018-05-02
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KeyWord:Antarctic krill oil  Auxiliary lipid-lowering  Hyperlipidemia  Unsaturated fatty acid
           
AuthorInstitution
孙昌华 山东省食品药品检验研究院
祝清芬 山东省食品药品检验研究院
王娜 济南极源生物科技有限公司
赵德明 中国农业大学
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Abstract:
      Abstract: To study the effect of auxiliary lipid-lowering function of preventive and therapeutic administration of Antarctic krill oil on experimental hyperlipidemic rats. Methods: We established hyperlipidemia model in SD rats that administrated of Antarctic krill oil for prevention and treatment respectively, then measured and analyzed the serum concentration of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C). Results: Antarctic krill oil preventive administration can significantly reduce serum TC, LDL-C(p<0.05), which confirms with the results of liver pathology mutually, while no significant change of serum TG and HDL-C(p>0.05). There was no significant statistical difference in serum concentration of TC, TG, HDL-C and LDL-C(p>0.05) and no effect on auxiliary lipid-lowering after Antarctic krill oil therapeutic administration.Conclusion: There was significant effect on auxiliary lipid-lowering and reducing of TC after Antarctic krill oil preventive administration.
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