Objective To investigate the effects of sand therapy temperature on bone reconstruction and numerical study on the heat transfer. Methods CT scan imaging was performed respectively for four times (before and after OA model was set up, and after the first and second weeks during the sand therapy). Import the scan data to MIMICS software, and the changes of femoral bone mass layer were analyzed. After combining the muscle, femur, bone marrow and meshing, the established three-dimensional model of the STL format was introduced into the COMSOL software for heat transfer simulation and effect of stress on bone remodeling induced by temperature field. Results Changes of four CT scan data were analyzed. The soft bone volume was reduced, while the dense and hard bone volume were increased. Numerical simulation on the heat transfer showed the temperature distribution of the thigh and the femur. Conclusions The thermal stress produced by sand therapy temperature exert promoting effect on the femur bone remodeling.