Establishment of a mouse model of pulmonary fibrosis induced by single intraperitoneal injection of paraquat
  
View Full Text  View/Add Comment  Download reader
DOI:
KeyWord:Pulmonary fibrosis;Paraquat;Intoxication;Animal model;
DONG Xue-song,LIU Sheng-ye,LIU Wei,LIU Shu-ying,LIU Zhi
DONG Xue-song1,LIU Sheng-ye2,LIU Wei1,LIU Shu-ying1,LIU Zhi1(1.Department of Emergency,The First Affiliated Hospital,China Medical University,Shenyang 110001,China,2.Seven-Year Clinical Medicine Program at China Medical University,Shenyang 110001)
Hits: 455
Download times: 2
Abstract:
      Objective To develop an easy and simple method of establishing mouse model of paraquat-induced pulmonary fibrosis.Methods Thirty-three C57BL/6J mice were divided randomly into the experimental group(n=30)and control group(n=3).Paraquat(10 mg/kg) was administrated to the animals of the experimental group by a single intraperitoneal injection.The mice were killed on the day 2,5,7,14 and 28 after paraquat administration.The mice in the control group were treated by an intraperitoneal injection of physiological...
Close
function PdfOpen(url){ var win="toolbar=no,location=no,directories=no,status=yes,menubar=yes,scrollbars=yes,resizable=yes"; window.open(url,"",win); } function openWin(url,w,h){ var win="toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=yes,resizable=no,width=" + w + ",height=" + h; controlWindow=window.open(url,"",win); } &et=909BCF45EAE28FE889FFC352FC5C360F015BD85A4F064474BA31062F1909E5CFE4ED33A814BB4168BC4F433865B7CADEEC021C08F2F5791FA8F55E5E721D7BEFEE6A67154ACC8C6446E037E942D5CBEBDE70DDAF2FD04208BD6FB6D5DA715DF1A7947BB34A535DEA8D05ABCDC7F6D8B1&pcid=&cid=&jid=&yid=9377ED8094509821&aid=99963042278&vid=&iid=E158A972A605785F&sid=&eid=&fileno=20110484&flag=1&is_more=0"> var my_pcid=""; var my_cid=""; var my_jid=""; var my_yid="9377ED8094509821"; var my_aid="99963042278";