Objective To establish a rat model of bronchial asthma combined with depression.Methods Twenty-two Wistar rats were randomly divided into control group and model group.The latter were sensitized with ovalbumin for 4 weeks and followed by CUMS for 4 weeks.Pathological changes of the lung tissue were observed by light microscopy and transmission electron microscopy.Eosinophil count and other inflammatory cell count in bronchoalveolar lavage fluid(BALF)were performed.The changes of behavior were detected by op...