The Establishment of a Rat Model for the Studies on the Relationship between Estrogen and Immunity by X-ray Irridiated Ovaries
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KeyWord:X-ray irradiation Estradiol Ovary Interleukin 2
Huang Hui
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      A rat model of lack of estradiol ( E2 ) was established by X-ray irradiation to ovaries. It was found that the reduction of E2 level in serum, increase of interleukin 2 ( IL-2 ) secretion and hyperplasia of lymphocytes. There was also a negative correlation between the level of E2 in serum and IL-2 production(r= -0.952, P<0.0005). The model would be a good subject for the associated research between estrogen and immune system.
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