医药学实验室潜在的生物安全风险与防范措施
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中国医学科学院药物研究所

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Potential risks of biosafety and prevention strategies in medical and pharmaceutical research laboratories
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Institute of Materia Medica Chinese Academy of Medical Science,Equipment Purchase Department

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    摘要:

    医药学研究实验室涉及的研究领域十分宽泛,实验中应用的包括动物、微生物及纳米颗粒物等多种材料,所产生的废弃物也日益增多,存在着一定的生物安全隐患。本文概述了基因扩增、基因重组、病原微生物研究、纳米研究、动物实验、基因编辑动物及实验废弃物等的潜在安全风险,提出了从制定严格的规章管理制度和完善硬件设施、加强教育培训、增强安全防范意识为主导的实验室生物安全风险防范措施。

    Abstract:

    Medical and pharmaceutical research laboratory usually involves wide range of study aspects. The materials used in the laboratory are various, including animals, microorganisms and nano-particles and other kinds. Meanwhile, with the production of more and more waste, more biosafety risks would be created. Here, we outlined the potential safety risks related with gene amplification, gene recombination, pathogenic microorganism research, nanotechnology, animal experiments, genetically altered animals, and experimental waste, etc. It also proposed preventive measures for laboratory biosafety risks, which mainly associate with developing strict legal frameworks, bettering hardware infrastructure, strengthening safety awareness, and enhancing education and training programs.

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  • 收稿日期:2024-03-18
  • 最后修改日期:2024-03-23
  • 录用日期:2024-04-12
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