恶性间皮瘤动物模型的研究进展
作者:
作者单位:

1.甘肃中医药大学 第一临床医学院,兰州 730000;2.甘肃省人民医院 胸外科,兰州 730000

作者简介:

通讯作者:

中图分类号:

R-33

基金项目:


Research progress on animal models of malignant mesothelioma
Author:
Affiliation:

1. the First Clinical Department of Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China.2. Department of Thoracic Surgery, Gansu Provincial People’s Hospital, Lanzhou 730000

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    恶性间皮瘤(malignant mesothelioma,MM)病例罕见且潜伏期长,临床上很难开展研究。动物模型的建立对于MM实验研究开展以及机制阐明具有重要意义。常见的动物模型主要包括自发性、诱发性、移植性和基因工程模型,但不同动物模型的适用范围各有不同。本文通过回顾国内外近十年来MM动物模型相关的实验研究,从造模方法、造模结果、模型优缺点3个方面总结和分析4种MM相关动物模型构建的最新进展,为基于动物模型开展的MM基础研究提供参考依据。

    Abstract:

    Malignant mesothelioma cases are rare and have a long incubation period, making the disease a difficult subject to clinically research. Animal models of malignant mesothelioma are crucial for experimental research and elucidating the pathogenesis of malignant mesothelioma. Common animal models include spontaneous, inducible, transplantable, and genetically engineered models, but the applicability of different animal models varies. This article reviews studies related to the establishment of animal models of malignant mesothelioma published in the past 10 years. Recent progress made in the establishment of four animal models of malignant mesothelioma is summarized from three aspects: modeling method, modeling result, and model advantages and disadvantages. This review summarizes and analyzes the current progress made in the establishment of animal models of malignant mesothelioma and thus provides a reference for basic malignant mesothelioma research using animal models.

    参考文献
    相似文献
    引证文献
引用本文

雍 盛,金大成,董信春,苟云久.恶性间皮瘤动物模型的研究进展[J].中国比较医学杂志,2024,34(9):137~145.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2024-03-07
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2024-10-30
  • 出版日期:
防诈骗提示!请勿点击不明链接或添加个人微信。编辑部所有邮箱后缀均为@cnilas.org
关闭