Effects of 4 weeks resistance training on hypoxic induced skeletal muscle atrophy in rats
投稿时间:2018-03-30  修订日期:2018-04-21
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KeyWord:SD rats, skeletal muscle atrophy, hypoxia, resistance training
于加倍 北京体育大学
胡扬 北京体育大学
李燕春 北京体育大学
梅涛 北京体育大学
韩天雨 北京体育大学
白学成 北京体育大学
付鹏宇 北京体育大学
朱镕鑫 北京体育大学
车欣媛 北京体育大学
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      【Abstract】Objective This study aimed to explore the effects of resistance training on hypoxic induced skeletal muscle atrophy in rats and provide theoretical basis to solve the problem of skeletal muscle atrophy of athletes in altitude training . Methods 24 male 8-week-old SD rats (mean body weight 230g) were divided into 4 groups: Normoxia control group (C), Resistance training group (R), Hypoxia group (H) and Hypoxia Resistance training group (HR). H and HR group were placed into simulated 4000 m altitude (12.4%, O2%). Moreover, R and HR group received resistance training. After 4 weeks hypoxia and resistance training intervention, body composition, the wet weight of skeletal muscle (soleus, musculus gastrocnemius, extensor digitorum longus and musculus biceps brachii) and skeletal muscle cross-sectional area (CSA) were measured. Results The muscle mass of HR group was significantly higher than H group. The wet weight and CSA of musculus biceps brachii in HR group were also higher than H group obviously. Conclusion Resistance training can help prevent the occurrence of skeletal muscle atrophy induced by hypoxia. Resistance ladder training can stimulate the hypertrophy of biceps.
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