Research progress on animal models of insomnia and evaluation methods
Received:September 13, 2021  
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DOI:10. 3969 / j.issn.1005-4847. 2022. 03. 017
KeyWord:insomnia; animal models; evaluation methods
夏天吉 中国医学科学院北京协和医学院药用植物研究所,北京
闫明珠 中国医学科学院北京协和医学院药用植物研究所,北京
王智 中国医学科学院北京协和医学院药用植物研究所,北京
靳苏维 中国医学科学院北京协和医学院药用植物研究所,北京
刘新民 中国医学科学院北京协和医学院药用植物研究所,北京
潘瑞乐 中国医学科学院北京协和医学院药用植物研究所,北京
常琪 中国医学科学院北京协和医学院药用植物研究所,北京
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      Data released by the Chinese Sleep Medicine Congress in 2021 showed that more than 300 million people in China have sleep disorders, of which insomnia is the most common. Research into the mechanisms of insomnia and candidate therapeutic drugs needs to involve insomnia animal models and appropriate evaluation method. This article summarizes aspects of the insomnia animal models commonly used in the past 10 years and classifies them from the perspective of physical, chemical, pathological, and multiple factors. The method used to evaluate the insomnia models are also outlined. This paper provides a resource for studies of insomnia.
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