Advances in mouse models of Campylobacter jejuni infection
Received:June 24, 2020  
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DOI:10. 3969 / j.issn.1005-4847. 2021. 01. 018
KeyWord:Campylobacter jejuni; mouse model; infection model; influence factor
        
AuthorInstitution
程雪婷 1.武汉大学中南医院,武汉 ; 2. 武汉大学同仁医院,武汉
陈妍灵 武汉大学中南医院,武汉
黄晓东 武汉大学同仁医院,武汉
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Abstract:
      Campylobacter jejuni can cause foodborne gastrointestinal diseases and has an important impact on human health. However, establishment of a mouse infection model is currently an obstacle for research of this bacterium. This article reviews the key factors that affect the establishment of the C. jejuni infection model, including strain virulence factors, mouse breeds, immune function, intestinal flora, diet composition and host adaptation, among others, in order to provide a reference for the successful establishment of a suitable mouse infection model.
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