Parkinson’ s disease ( PD) is a serious neurodegenerative disease. Typical pathological changes associated with PD are cellular necrosis and the loss of dopaminergic neurons in many areas of brain, as well as the appearance of multiple dyskinesias. Although the etiology of PD has not been clarified, the use of animal models plays a vital role in investigating the mechanisms of PD. In this article, we review the characteristics of different animal models of PD, discuss the characteristics of different animal species, and compare the clinical differences between animal models and PD patients to provide fundamental support for future PD research.