Progress in the application of adipose-derived mesenchymal stem cells in animal models
Received:May 05, 2019  
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DOI:10. 3969 / j.issn.1005-4847. 2019. 06. 019
KeyWord:adipose-derived mesenchymal stem cells; mouse disease model; application therapy
杜珍珍 黑龙江八一农垦大学动物科技学院,黑龙江大庆
徐郑美 黑龙江八一农垦大学动物科技学院,黑龙江大庆
司琳清 黑龙江八一农垦大学动物科技学院,黑龙江大庆
曹立明 黑龙江八一农垦大学动物科技学院,黑龙江大庆
刘庆 黑龙江八一农垦大学动物科技学院,黑龙江大庆
鲁文赓 黑龙江八一农垦大学动物科技学院,黑龙江大庆
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      Stem cells are known as the “ universal cells” in medicine. With the development of medical technology, the method for treating diseases are constantly being updated. Based on the advantages of adipose mesenchymal stem cells (i.e., they are easy to obtain, easy to amplify in vitro, and cause less ethical controversy), an increasing number of researchers focus on this type of stem cells. Therefore, the application of adipose-derived mesenchymal stem cells in animal models is more and more. This article introduces the clinical application of a typical mouse disease model, analyzes the therapeutic effect of adipose-derived mesenchymal stem cells on the disease, and concludes that adiposederived mesenchymal stem cells can differentiate in many ways by secreting cytokines. Based on clinical research and the application of adipose mesenchymal stem cells, immunomodulation may play a role in the treatment of many kinds of diseases.
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