Research progress on animal models of low-back pain
Received:November 23, 2018  
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DOI:10. 3969 / j.issn.1005-4847. 2019. 03. 020
KeyWord:low-back pain; lumbar disk herniation; lumbar facet arthritis; animal models
李赫桐 华北理工大学附属医院骨科,唐山
勾禹 河北医科大学研究生院,石家庄
田发明 华北理工大学医学实验研究中心,唐山
张柳 1. 华北理工大学附属医院骨科,唐山 ; 2. 煤炭总医院,北京
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      Low-back pain (LBP) is common and the cure rate is low. Its mechanism of action is incompletelyunderstood and may be related to degeneration of intervertebral disks, facet-joint injury, or inflammation of muscle fascia.Establishing an appropriate animal model can help to study and understand the pathogenesis of LBP, as well as explore itsprevention and treatment methods. This article summarizes the research progress of animal models which can be used to induce low-back pain.
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