Effects of sampling parameters on electrocardiogram waveforms in mice
Received:April 28, 2018  
View Full Text  View/Add Comment  Download reader
DOI:10. 3969 / j.issn.1005-4847. 2019. 02. 017
KeyWord:mouse; sampling parameter; electrocardiogram; method; filter; stability
           
AuthorInstitution
孙权 中南大学湘雅医院心血管内科,长沙
邱雪婷 中南大学湘雅医院老年病科,长沙
李传昶 中南大学湘雅医院老年病科,长沙
周正适 中南大学湘雅医学院实验动物学部,长沙
Hits: 1374
Download times: 363
Abstract:
      Objective To evaluate the effects of sampling parameters on electrocardiogram (ECG) waveforms inmice. Methods C57 mice were anesthetized with sodium pentobarbital and needle electrodes were placed subcutaneouslyin their limbs. ECG signals were sampled, recorded and analyzed with different sampling parameters using a RM6240BDmulti-channel physiological recording system. Results The sampling rate, low-pass filter, time constant, and notch filterhad different effects on ECG waveforms. Some parameters led to various deformation and distortion of the ECG signals.Conclusions Appropriate sampling parameters should be applied in ECG experiments in mice to obtain accurate results.An improved surgical technique is preferred to acquire stable ECG signals instead of filtering or digital smoothing.
Close
function PdfOpen(url){ var win="toolbar=no,location=no,directories=no,status=yes,menubar=yes,scrollbars=yes,resizable=yes"; window.open(url,"",win); } function openWin(url,w,h){ var win="toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=yes,resizable=no,width=" + w + ",height=" + h; controlWindow=window.open(url,"",win); } &et=970261AF74811A5DF4536B3CA403EAA9CCC5DCE951B538F30856FAA55F322D3796C0D40A73F884B25F3846F5698EFFC00A24936341B58185BA1836C1D0687DC7FE15A7BD3F385481&pcid=&cid=&jid=&yid=B6351343F4791CA3&aid=&vid=&iid=0B39A22176CE99FB&sid=FBCA02DBD05BD4EA&eid=6A73B36E85DB0CE9&fileno=201902017&flag=1&is_more=0"> var my_pcid=""; var my_cid=""; var my_jid=""; var my_yid="B6351343F4791CA3"; var my_aid="";