Diabetic foot with diabetic peripheral neuropathy (DPN) can lead to peripheral nerve dysfunction. Exploring appropriate animal models of the disease can make a better understanding of the occurrence, development, pathogenesis, prevention and treatment of DPN. Therefore, a reasonable construction of animal models is related to the success of experimental research. Up to date, experimental animals used in the research of diabetic foot neuropathy include rats, nude mice, transgenic mice, and so on. Nerve injury models can be generated by different means, such as ischemia reperfusion, resection or ligation of nerves and scalds. This article will review the recent research progress of diabetic foot neuropathy animal models.