Abstract:Heat stress which leads to a state of temperature imbalance caused by long-term exposure of the body in a thermal environment and the body could not adequately dissipate heat. With the progress of the miRNA measurement technology, many scholars had found that heat stress can lead to a change in the miRNA. expression miRNA can bind its target genes to inhibit the expression of its target genes. That made miRNA to play an important role in the regulation of the body's life activities and anti-heat stress.