Research progress of tree shrew models of viral hepatitis and modeling strategy
Received:January 14, 2014  
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DOI:10.3969/j.issn.1005-4847.2014.02.0020
KeyWord:Viral hepatitis;Hepatitis B virus;Hepatitis C virus;Tree shrews;Animal model
                 
AuthorInstitution
庞义全 昆明理工大学生命科学与技术学院, 昆明
冯悦 昆明理工大学生命科学与技术学院, 昆明
孙晓梅 中国医学科学院医学生物学研究所, 昆明
刘丽 昆明理工大学生命科学与技术学院, 昆明
代解杰 中国医学科学院医学生物学研究所, 昆明
夏雪山 昆明理工大学生命科学与技术学院, 昆明
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Abstract:
      Viral hepatitis is a major liver disease caused by virus infection. Viral hepatitis is popular in China, mainly caused by hepatitis B and hepatitis C viruses. Experimental animal model is a necessary platform for the research on mechanism of viral infection and pathogenicity, for treatment and vaccine development. Up to date, a great progress in the development of viral hepatitis animal models has been achieved in spite of the most of findings are limited to hepatitis B and C. Here, we summarize the recent findings of viral hepatitis animal models, focusing on the tree shrew animal model and its modeling strategy.
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