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| Research progress of tree shrew models of viral hepatitis and modeling strategy |
| Received:January 14, 2014 |
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| DOI：10.3969/j.issn.1005-4847.2014.02.0020 |
| KeyWord:Viral hepatitis;Hepatitis B virus;Hepatitis C virus;Tree shrews;Animal model |
| Author | Institution |
| 庞义全 |
昆明理工大学生命科学与技术学院, 昆明 |
| 冯悦 |
昆明理工大学生命科学与技术学院, 昆明 |
| 孙晓梅 |
中国医学科学院医学生物学研究所, 昆明 |
| 刘丽 |
昆明理工大学生命科学与技术学院, 昆明 |
| 代解杰 |
中国医学科学院医学生物学研究所, 昆明 |
| 夏雪山 |
昆明理工大学生命科学与技术学院, 昆明 |
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| Abstract: |
| Viral hepatitis is a major liver disease caused by virus infection. Viral hepatitis is popular in China, mainly caused by hepatitis B and hepatitis C viruses. Experimental animal model is a necessary platform for the research on mechanism of viral infection and pathogenicity, for treatment and vaccine development. Up to date, a great progress in the development of viral hepatitis animal models has been achieved in spite of the most of findings are limited to hepatitis B and C. Here, we summarize the recent findings of viral hepatitis animal models, focusing on the tree shrew animal model and its modeling strategy. |
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