Abstract:Objective To evaluate the inhibitory effect and toxicity of juglone administered via different routes on the nude mice model bearing subcutaneously transplanted tumor.Methods Human hepatocellular carcinoma BEL-7402 cells were subcutaneously injected into nude mice.The resultant tumors were taken and prepared into small tissue blocks,which were implanted subcutaneously into nude mice to establish mouse models bearing human hepatoma.Juglone was administered at different doses by intraperitoneal injection and ...