MicroPET observation of the effect of curcumin on cerebral glucose metabolism in APPswe/PS1dE9 double transgenic mice
  
View Full Text  View/Add Comment  Download reader
DOI:
KeyWord:microPET;18F-FDG;Cerebral glucose metabolism;Curcumin;APPswe/PS1dE9 double transgenic mice;
WANG Hong,GAO Kai,LI Rui-sheng,REN Ying,ZHU Zhi-hui,SUN Hai-yun,YANG Jin-duo,WANG Peng-wen
WANG Hong1,GAO Kai2,LI Rui-sheng1,REN Ying1,ZHU Zhi-hui1,SUN Hai-yun1,YANG Jin-duo1,WANG Peng-wen(1.Laboratory of Pharmacology of Traditional Chinese Medicine,Dongzhimen Hospital,BUCM,Beijing 100700,China,2.Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences & Comparative Medical Center,Peking Union Medical College,Beijing 100021,China)
Hits: 425
Download times: 0
Abstract:
      Objective To observe the status of cerebral glucose metabolism in normal control group mice,APP/PS1 double transgenic mice of model group and curcumin treatment group by 18F-FDG microPET.Methods APP/PS1 dtg mice from the model group,curcumin treatment group,and normal C57BL/6J mice with the same background were randomly selected(age: 6 months;n=3)for microPET study.Each mouse was anesthetized using 2% isoflurane and was injected through a tail vein with 14.8-16.5 MBq 18F-FDG as a bolus.After 45-minute of 18...
Close
function PdfOpen(url){ var win="toolbar=no,location=no,directories=no,status=yes,menubar=yes,scrollbars=yes,resizable=yes"; window.open(url,"",win); } function openWin(url,w,h){ var win="toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=yes,resizable=no,width=" + w + ",height=" + h; controlWindow=window.open(url,"",win); } &et=956BC102916CB26FA69A2884C9C313F95987A1F56611F74A88EECF32DD3E68C196E7464644005F211B1149676F89CF4DA68B6747BF5A2062165C5F280F75427777EFA1CEADD08C617F04984883E2BD242F37F54C6469516D080D2F55F0E961D81875C23974255CCADF8FB9D062E9DDFF061D6C646B7FE67A&pcid=&cid=&jid=&yid=9377ED8094509821&aid=99963042274&vid=&iid=E158A972A605785F&sid=&eid=&fileno=20110480&flag=1&is_more=0"> var my_pcid=""; var my_cid=""; var my_jid=""; var my_yid="9377ED8094509821"; var my_aid="99963042274";