Objective To investigate the changes of TLR4 and CD14 mRNA expression in the rats with acute lung injury(ALI) induced by lipopolysaccharide(LPS).Methods Twenty-four male Wistar rats were randomly divided into two groups: normal control group and LPS model group.Each group had two subgroups,4 hours and 8 hours after LPS injection.The ALI model was established by intravenous injection of LPS(10 mg/kg) through the tail vein.The arterial blood gas graph(ABGG) and lung-body index were analyzed.The expressions of...