Abstract:Objective To select and establish suitable experimental animal models of skeletal fluorosis and analyze their sensitivity to fluoride-induced bone damages.Methods New Zealand rabbits,Hartley white guinea-pigs,Wistar rats,and Kunming mice(16 each) were included in this study.Each kind of the animals were divided randomly into two groups(each group 8): control group(group C) fed with standard food and distilled water,and model group(group M) fed with normal food and 150 mg/L NaF distilled water).At 60 days af...