Objective To explore the effects of multi-intervention RAAS on ventricular remodeling and serum K+ concentration in the chronic pressure overload heart due to cardiac insufficiency in rats.Methods To establish chronic cardiac insufficiency animal models with suprarenal abdominal aortic banding in rats.Six-week old female Sprague-Dawley rats were enrolled and the suprarenal abdominal aorta was ligated by 4-0 nylon suture against a needle(outer diameter 0.7 mm).Twenty female rats were randomized into four gro...