Abstract:Myostatin(MSTN)is an important transcriptional regulation factor in the development of animal muscle growth.There are several factors,such as MyoD and FoxO,regulating the transcription of MSTN gene.MSTN protein expressed in skeletal muscle cells is activated by metalloproteinase in blood circulation system,and is able to bind with the receptors on targeting cell membrane to activate the cellular signal transduction pathway.MSTN with other transcriptional regulation factors can cause different physiologic ef...