Viral Safety Risks Posed by PERVs in Xenotransplantation
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R617

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    Abstract:

    Pig to human xenotransplantation could potentially alleviate the shortage of human organs.However,porcine endogenous retroviruses(PERVs) which are present in the germline of pigs as proviruses could hardly be eliminated.PERV would be transferred to the human recipient along with xenografts.In a worst-case scenario,this might result in the emergence of a new viral disease.This report reviewed research on viral safety risks posed by PERVs in xenotransplantation as well as research on PERV from Chinese miniatu...

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