Application of Cre/Loxp and Tet System in the Gene Controlled Expression
DOI:
Author:
Affiliation:

Clc Number:

R346

Fund Project:

  • Article
  • |
  • Figures
  • |
  • Metrics
  • |
  • Reference
  • |
  • Related
  • |
  • Cited by
  • |
  • Materials
  • |
  • Comments
    Abstract:

    In the research of transgenic mice models,the controlled expression of target gene is very important to the application of the transgenic mice models.The implement of the expression of the transgene in time and in space has got great progress.This article introduces the principles,application,progresses in research of Tet system and the Cre/LoxP system,and presents the strong and weak points of those two control systems.The focal point is the outcome of the combined application of those two systems.Furthermore,to introduce the application of Cre/Loxp system in directional expression of HPV11 complete gene in mice.Accordingly,put forward an assumption to solve the problem of orientation expression of the multi-gene.

    Reference
    Related
    Cited by
Get Citation
Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:
  • Revised:August 22,2006
  • Adopted:
  • Online:
  • Published: