Establishment of the Model for Multichannel Gastric Electrical Stimulation and Gastric Emptying in Dogs
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R332

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    Abstract:

    Objective To set up the model of multiple channels gastric electrical stimulation and gastric emptying. Methods\ Twelve British Beagle dogs were involved in this study .Four pairs of bipolar electrodes were implanted on the stomach serosa along the greater curvature . A jejunal cannula was implanted 20cm beyond the pylorus for the assessment of gastric emptying. Results\ 1. Chyme was easily collected from the jejunal cannula, which represented the effect of various gastric electrical stimulation and various stimulation parameters on gastric motility. 2. Gastric slow waves were recorded clearly and steadily via gastric serosal multiple electrodes. It could record a variety of gastric slow wave in various experiments and various periods. 3. Single_channel and multi_channel electrical stimulation of long pulse via stomach serosal electrodes was able to entrain gastric slow wave. Conclusion\ Multiple channels gastric electrical stimulation is an available method for investigating gastric electrophysiology, gastric pacing and effect of gastric pacing on gastric emptying. British Beagle dogs are ideal materials for this model.

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  • Received:
  • Revised:April 21,2004
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