Investigation of Source of SARS Virus in Laboratory Animals and Zoo Animals
  Revised:December 16, 2003
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KeyWord:Severe Acute Respiratory Syndrome,Coronavirus,Laboratory animals,Zoo animals
LIU Zhong-hua,CHENG Shu-jun,GAO Zhong-ming,QU Li-zhi,WEI Se-lin,GU Wei-wang,HUANG Run
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Abstract:
      ObjectiveTo investigate SARS virus in animals . MethodsThe secretions of respiratory t ract and swallow swab were examined by using nested RT-PCR,and the sera were det ected by ELISA. Result and conclusion84 swab samples w ere collected from monkeys, dogs, paguma larvata, etc. No SARS coronavirus s equen ces were amplified from these samples. Murine coronavirus antibody of 52 sera i s positive from 373 mice sera and 198 rat sera detected by ELISA. Investigation of source of SARS is very important for the managemetn of SARS.
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