Study on Infectivity of Pasteurella pneumotropica in Laboratory Rats and Mice
  Revised:December 25, 2002
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LIU Xing,LI Hong,SHI Chao_hui,ZHANG Li_fang
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      Objective To study the infectivity of Pasteurella pneumotropica (P.pneumotropica) from different sources between laboratory rats and mice. Methods 30 laboratory rats and mice were inoculated with 3 %P.pneumotropica% isolates from rats, mice and wild mice, to compare the biologic characteristics, by SDS_PAGE, Western blot and RAPD_PCR, of the 3 isolates at different days of post_inoculation with that before inoculation. Results Laboratory rats and mice were infected easily by 3 %P.pneumotropica% isolates, which were carried in them until the end of the test (4w). lsolates reobtained from post_inoculated animals had no difference distinctly in biologic characteristic, protein component, antigenic bands and genotype. Conclusion The same isolate of %P.pneumotropica% can infect both laboratory rats and mice.
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