Establishment of a Model of Explosive Open Abdominal Injury and Study of Risky Factors of Early Death
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R-332

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    Abstract:

    Objective To establish a model of explosive abdominal injury and seawater immersion and to study the risky factors of early death. Methods Thirty healthy dogs were divided into two groups: experimental group(explosive abdominal injury and seawater immersion)and control group(explosive open abdominal injury only). Blood samples were taken at eight different time intervals for assessing blood gas, plasma osmotic pressure and serum electrolytes. The hemodynamic and respiratory changes were recorded. At the end of study lung was harvested for pathologic examination. Results Post_trauma condition in experimental group was more serious than that in control group. Progressive dysfunction of respiratory and circulatory system, acute lung injury, severe hypernatremia and higher osmotic pressure were found only in experimental group. The mean survival time in experimental group was 209 minutes. Conclusion The results of this study indicates that the explosive model of abdominal injury is practicable and can be repeated well. Seawater immersion after open pneumothorax could result in severe physiopathologic changes. These risky factors appear to be associated with early death in experimental models.

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  • Received:
  • Revised:January 27,2003
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