| 孙昌华,祝清芬,王娜,赵德明.南极磷虾油辅助降血脂预防与治疗作用的比较研究[J].中国实验动物学报,,():. |
| 南极磷虾油辅助降血脂预防与治疗作用的比较研究 |
| A comparative study of auxiliary lipid-lowering function of Antarctic krill oil preventive and therapeutic administration |
| 投稿时间：2018-03-20 修订日期：2018-05-02 |
| DOI： |
| 中文关键词: 南极磷虾油 辅助降血脂 高血脂症 不饱和脂肪酸 |
| 英文关键词:Antarctic krill oil Auxiliary lipid-lowering Hyperlipidemia Unsaturated fatty acid |
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| 摘要点击次数: 113137 |
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| 中文摘要: |
| 摘 要：目的：研究南极磷虾油对实验性高血脂大鼠预防和治疗给药辅助降血脂作用效果。方法：建立SD大鼠高脂血症模型，预防及治疗给予南极磷虾油，检测分析对大鼠血清总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)的影响。结果：南极磷虾油预防给药可显著降低大鼠血清TC、LDL-C(p＜0.05)且与肝脏病理学检查结果相互印证。但对大鼠血清TG、HDL-C的影响不明显(p＞0.05)；虾油治疗给药未见大鼠血清TC、TG、HDL-C、LDL-C明显下降(p＞0.05)，辅助降血脂作用效果不明显。结论：南极磷虾油辅助降血脂作用预防性给药效果明显，具有显著降低血脂TC的作用。 |
| 英文摘要: |
| Abstract: To study the effect of auxiliary lipid-lowering function of preventive and therapeutic administration of Antarctic krill oil on experimental hyperlipidemic rats. Methods: We established hyperlipidemia model in SD rats that administrated of Antarctic krill oil for prevention and treatment respectively, then measured and analyzed the serum concentration of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C). Results: Antarctic krill oil preventive administration can significantly reduce serum TC, LDL-C(p＜0.05), which confirms with the results of liver pathology mutually, while no significant change of serum TG and HDL-C(p＞0.05). There was no significant statistical difference in serum concentration of TC, TG, HDL-C and LDL-C(p＞0.05) and no effect on auxiliary lipid-lowering after Antarctic krill oil therapeutic administration.Conclusion: There was significant effect on auxiliary lipid-lowering and reducing of TC after Antarctic krill oil preventive administration. |
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